منابع مشابه
The Periaqueductal Gray (PAG)
This issue covers a broad territory of PAG function: neu-ropharmacology, functional organization, and PAG plasticity in adaptive behavior, emotion, anxiety, and the less-studied plasticity of the PAG function in females. Interest in the involvement of PAG in defensive behavior has a long history. Thinking about this area was radically changed by the seminal contributions of Bandler and DePaulis...
متن کاملTRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons.
The purpose of this study was to determine the role of transient receptor potential vanilloid type 1 (TRPV1) receptor in modulating neuronal activity of the dorsolateral periaqueductal gray (dl-PAG) through excitatory and inhibitory synaptic inputs. First, whole cell voltage-clamp recording was performed to obtain the spontaneous miniature excitatory postsynaptic currents (mEPSCs) and inhibitor...
متن کاملPERIAQUEDUCTAL GRAY 1 Running head: PERIAQUEDUCTAL GRAY Common representation of pain and negative emotion in the midbrain periaqueductal gray
Human neuroimaging offers a powerful way to connect animal and human research on emotion, with profound implications for psychological science. However, the gulf between animal and human studies remains a formidable obstacle: Human studies typically focus on the cortex and a few subcortical regions such as the amygdala, whereas deeper structures such as the brainstem periaqueductal gray (PAG) p...
متن کاملSerotonin, the periaqueductal gray and panic.
This article reviews experimental evidence and theoretical constructs that implicate serotonin (5-HT) modulation of defensive behavior within the midbrain periaqueductal gray in panic disorder (PD). Evidence with conflict tests in experimental animals indicates that 5-HT enhances anxiety, whereas results with aversive stimulation of the dorsal periaqueductal gray point to an anxiolytic role of ...
متن کاملCannabinoids, anxiety, and the periaqueductal gray
The use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties. As scientific research methods developed, the cannabinoids present in this herb were characterized, as well as their complex interface with the human central nervous system, provided by the activation of specific receptors. The subsequent description of an end...
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ژورنال
عنوان ژورنال: Neural Plasticity
سال: 2009
ISSN: 2090-5904,1687-5443
DOI: 10.1155/2009/360907